Cirrhosis

Fetal Cells in Liver after Pregnancy May be Cause of Cholestatic Liver Disease

Published in Women's Health Weekly, January 11th, 2001

Scientists report in the Journal of Hepatology that a serious liver ailment known to predominantly affect middle-aged women may be caused by fetal cells in the women's livers that remain after pregnancy.

Microchimerism, or the presence of fetal cells that remain in maternal tissues or blood after pregnancy, also occurs when donor cells are grafted into a host recipient. Scientists report that primary biliary cirrhosis has manifestations similar to those seen in hepatic graft-versus-host disease.

"Primary biliary cirrhosis is a chronic cholestatic liver disease characterized by progressive inflammatory destruction of bile ducts, with eventual...

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Source: Women's Health Weekly (2001-01-11)

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