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Obstetrics

Despite Earlier Warnings, Study Finds No Increased Risk From Cough Suppressant Use

Published in Women's Health Weekly, March 15th, 2001

Despite earlier warnings based on animal research, a new controlled study found no extra risk of major malformations in infants of women who took dextromethorphan (DM), an active ingredient in over-the-counter common cough suppressants, during the first trimester of their pregnancy.

The results of the study were published in the February 2001 issue of Chest.

Although DM has been on the market for years, the new research findings represent the first controlled study in humans to specifically investigate this cough medication for safety during pregnancy. Prior to this investigation, a widely-publicized study based on chick embryo research had...

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