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Adiposity

Tamoxifen Associated With Fatty Liver And Build-Up Of Intra-Abdominal Fat In Obese Patients

Published in Women's Health Weekly, March 29th, 2001

by Jennifer Webb, staff medical writer - Fatty liver and intra-abdominal fat accumulation are common in obese patients receiving tamoxifen for the treatment of breast cancer, study results indicate.

"Tamoxifen is a nonsteroidal anti-estrogenic drug used for adjuvant treatment of breast cancer and recently as a chemo-preventative agent for breast cancer and, on an investigational basis, for other cancers," reported J.G. Kral and colleagues from the Southern University of New York.

The researchers noted that case reports of hypertriglyceridemia and fatty liver disease have been demonstrated in tamoxifen users.

A cross-sectional...

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