Breast Cancer

Inherited Variants Of Three Genes Affect Treatment Response And Outcome

Published in Women's Health Weekly, April 5th, 2001

In findings that support potential tailored therapy for patients with cancer and possibly other diseases, Duke University Medical Center researchers and colleagues report finding that inherited variants in three genes are associated with response to high-dose chemotherapy and overall survival in advanced breast cancer.

If future studies show that these genetic variants can predict response and outcome, a simple blood test and genetic analysis might help physicians select the best treatment options for each patient, the researchers said.

Besides breast cancer, this pre-treatment genotyping might be useful to tailor treatments for numerous other...

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Source: Women's Health Weekly (2001-04-05)

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