Gene Vectors

Therapy Containing Natural Inhibitor Controls Breast Cancer Metastasis

Published in Women's Health Weekly, October 11th, 2001

by Sonia Nichols, senior medical writer - Using an adenoviral vector expressing genes for the natural angiogenesis inhibitor angiostatin, medical researchers in Canada have prevented the formation of metastatic tumors in murine models of breast cancer.

The new research adds evidence to a growing belief that gene therapies preventing angiogenesis in targeted tissues could be used for treating a number of human diseases. Angiostatin, a protein obtained during plasminogen activity, is just one of a few angiogenesis inhibitors that scientists are investigating for their usefulness in curbing angiogenic processes.

"In this study, we have expressed the...

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Source: Women's Health Weekly (2001-10-11)

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