Breast Cancer

Antisense Therapy May Enhance Effects Of Chemotherapy

Published in Women's Health Weekly, December 13th, 2001

Antisense therapy shows promise in attacking two types of breast cancer and can enhance the effects of standard chemotherapy, according to a study from the University of Alabama at Birmingham and Hybridon, Inc., of Cambridge, Massachusetts.

Their work was published in the November 2001 issue of Clinical Cancer Research, a scientific journal. Antisense therapy is a relatively new way of attacking cancer cells. The antisense approach involves a specific drug that inhibits the expression of a cancer-causing gene known as MDM2.

The MDM2 gene is overexpressed in several human cancers, including breast, lung and colon cancer. MDM2 wreaks its...

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Source: Women's Health Weekly (2001-12-13)

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