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Osteoporosis

New data suggests that zoledronic acid increases bone density

Published in Women's Health Weekly, April 4th, 2002

A new study published in The New England Journal of Medicine demonstrates that the Novartis drug zoledronic acid, an intravenous bisphosphonate, significantly increases bone density in women with postmenopausal osteoporosis.

This is the first time that a bisphosphonate, given at intervals of up to 1 year between doses, has produced sustained suppression of bone turnover and an increase in bone mineral density in the spine and hip as great as that seen with oral daily or weekly dosing of other bisphosphonates.

"Oral bisphosphonates, although effective in treating osteoporosis, have complicated dosing requirements that can lead to compliance...

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