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Teratogens

Epilepsy drugs in pregnancy can triple risk of major malformation or developmental delay in children

Published in Women's Health Weekly, May 9th, 2002

Epilepsy drugs given to women during pregnancy can triple the risk of congenital malformation or developmental delay in their children, finds research in the Journal of Medical Genetics.

Stopping treatment for epilepsy during pregnancy is not an option, but there is an urgent need to develop safer drugs, concluded the researchers. Six in every 1000 pregnancies will be to a woman treated with epilepsy drugs.

One hundred forty-nine mothers being treated with antiepileptic drugs in the Grampian region of Scotland were studied - 58% of the total invited to take part. They had all given birth between 1976 and 2000.

In all,...

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