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Fetal Medicine

Animal study shows little maternal risk associated with fetal gene transfer

Published in Women's Health Weekly, May 16th, 2002

by Sonia Nichols, senior medical writer - Animal model experiments indicate fetal somatic gene transfer could be accomplished without harming the mother of the fetus, according to investigators in France.

Several studies have introduced the idea of treating fetuses in utero using somatic gene transfer. Yet, limitations and complications affecting the efficacy of such therapy are still unknown. D. Gallot and coauthors in the Laboratory for Molecular Oncology at the Centre Jean-Perrin in Clermont-Ferrand, France, announced the goal of their research "was to assess the integration and transcription of a proviral marker gene injected intraperitoneally into rat fetuses as...

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