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Breast Cancer

Genistein-containing supplements may stop tamoxifen

Published in Women's Health Weekly, May 30th, 2002

Isoflavone-enhanced dietary supplements containing genistein may negate the tumor-fighting effects of tamoxifen, a commonly prescribed medication for women battling estrogen-dependent breast cancer, according to new findings appearing in the May 1, 2002, issue of the journal Cancer Research.

The research was led by William G. Helferich, a professor of food science and human nutrition at the University of Illinois at Urbana-Champaign.

In a preclinical study, researchers divided 66 mice, with their ovaries removed, into 6 groups to monitor the effects of estrogen and various amounts of tamoxifen and genistein, an estrogen-like component found in...

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