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Women's Health Weekly

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Maternal Transmission



Profile for antigen processing may be linked to HCV protection in infants



July 4th, 2002

by Sonia Nichols, senior medical writer - Genotypic profiling of infants born of women infected with hepatitis C virus (HCV) shows that infants may be less prone for acquiring infection through vertical transmission when they have a specific class of human leukocyte antigen (HLA).

That class, HLA-DR13, may confer protection by increasing seroreversion in the infants of HCV-infected mothers, according to Isabella Bosi and colleagues, University of Bologna, Bologna, Italy.

In a study of vertical transmission, Bosi's team performed HLA typing on 35 infants, approximately half who had seroconverted, and on 20 mothers.

"Logistic...


Source: Women's Health Weekly (2002-07-04)

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