Heart Disease

Popular long-acting contraceptive linked to vascular dysfunction

Published in Women's Health Weekly, October 3rd, 2002

Long-term use of a contraceptive injected once every three months impairs the arteries' ability to contract and expand, possibly increasing the risk for heart disease, according to research reported in the September 3, 2002, rapid-access issue of Circulation: Journal of the American Heart Association.

Researchers studied depot medroxyprogesterone acetate (DMPA), commonly known by the brand name Depo-Provera. The drug affects the arteries' ability to "respond to different stimuli and particularly affects the ability of the artery to dilate," said senior author, Dudley J. Pennell, MD, a professor of cardiology at the Imperial College School of Medicine in London. ...

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Source: Women's Health Weekly (2002-10-03)

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