Weight Loss

Interleukin-18 associated with obesity

Published in Women's Health Weekly, October 24th, 2002

by Maria G. Essig, MS, ELS, senior medical writer - Plasma levels of interleukin-18 (IL-18) were reduced by weight loss, indicating an association between the cytokine and obesity, according to a report in the Journal of Clinical Endocrinology and Metabolism.

"Obesity is associated with an increased risk of developing atherosclerosis, which may be mediated, at least in part, by increased secretion of proinflammatory cytokines by adipose tissue," explained Katherine Esposito and colleagues at the Second University of Naples. "We examined the hypothesis that circulating levels of interleukin-18 were elevated in obese women and would be reduced by weight...

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Source: Women's Health Weekly (2002-10-24)

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