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Breast Cancer

University of Alabama to initiate phase I trial of HER-2 vaccine

Published in Women's Health Weekly, December 19th, 2002

Galenica Pharmaceuticals announced that the University of Alabama at Birmingham Comprehensive Cancer Center (UAB-CCC) is beginning a National Cancer Institute-sponsored phase I human clinical trial of a HER-2 vaccine containing Galenica's immune enhancer GPI-0100.

The trial will evaluate a therapeutic vaccine containing a HER-2 derived antigen designed by UAB and Ohio State University scientists together with Galenica's proprietary immune enhancer GPI-0100 to treat patients with HER-2 overexpressing cancers.

Preclinical studies showed that vaccination with this antigen, a synthetic peptide containing regions of the HER-2 receptor and the measles...

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