Ovarian Cancer
Tumor DNA detected in blood samples
Published in Women's Health Weekly, December 19th, 2002
The test is based on digital analysis of single nucleotide polymorphisms (SNP, or "snips"), in which investigators separate the two strands of code found in every gene to search for imbalances that are a hallmark of cancer cell DNA.
With 54 blood samples from late- and early-stage ovarian cancer patients, the Hopkins team used digital SNP analysis to find so-called "allelic imbalance" in 87% (13 out of 15) of early-stage ovarian cancers and 95% (37 out of 39) with late-stage disease. No allelic imbalance was detected in 31 blood samples...
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