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Women's Health Weekly

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Fertility Medicine



Ovary gene may explain certain aspects of infertility



December 26th, 2002

Harvard Medical School researchers have uncovered an ovary gene whose absence from mouse egg cells produced severe pregnancy complications.

The gene, Fmn2, which produces the protein formin-2, is similar in mice and humans and offers promise for understanding embryo loss, birth defects, and infertility in women.

"As humans we are incredibly bad at producing eggs with the normal number of chromosomes, which is the leading cause of pregnancy loss in women," said Benjamin Leader, an HMS MD/PhD candidate, and the paper's lead author. "The biological means for ensuring proper distribution of chromosomes to the egg has been difficult to determine.

...


Source: Women's Health Weekly (2002-12-26)

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