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Ovarian Cancer

Circulating IGF-1 levels are directly related to younger women's disease risk

Published in Women's Health Weekly, December 26th, 2002

Results of a recent study show a direct relationship between levels of circulating insulin-like growth factor and a woman's risk of developing ovarian cancer before age 55.

A. Lukanova and colleague at the International Agency for Cancer Research, Lyon, France, wrote: "Insulin-like growth factor (IGF)-1, a mitogenic and antiapoptotic peptide, has been implicated in the development of several cancers. We hypothesized that high circulating IGF-1 concentrations may be associated with an increased risk of ovarian cancer. A case-control study was nested within three prospective cohorts in New York (USA), Umea (Sweden), and Milan (Italy)."

Study...

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