Ovarian Cancer
Circulating IGF-1 levels are directly related to younger women's disease risk
Published in Women's Health Weekly, December 26th, 2002
A. Lukanova and colleague at the International Agency for Cancer Research, Lyon, France, wrote: "Insulin-like growth factor (IGF)-1, a mitogenic and antiapoptotic peptide, has been implicated in the development of several cancers. We hypothesized that high circulating IGF-1 concentrations may be associated with an increased risk of ovarian cancer. A case-control study was nested within three prospective cohorts in New York (USA), Umea (Sweden), and Milan (Italy)."
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