Breast Development

Novel method grows normal human breast tissues in vivo

Published in Women's Health Weekly, February 6th, 2003

Researchers have developed a new method for growing normal human breast tissues in mice.

They described "a novel system for studying the growth of normal human mammary epithelium in vivo as grafts in athymic nude mice. The key feature of this model is reconstitution of the epithelial-stromal interactions required for normal growth and differentiation of the human mammary epithelium, which produces ducts that are comparable to those in the normal human mammary gland."

"Human breast epithelial organoids were combined with mammary fibroblasts from mouse or human origin in collagen gels, which were subsequently transplanted under the renal capsule of...

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Source: Women's Health Weekly (2003-02-06)

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