Published in Women's Health Weekly, March 20th, 2003
According to recent research from Japan, "It is now well established that supraphysiological doses of 1alpha,25-dihydroxyvitamin D-3 [1alpha,25(OH)(2)D-3] stimulate bone resorption."
"Recent studies have established that osteoblasts/stromal cells express receptor activator of NF-kappaB ligand (RANKL) in response to several bone-resorbing factors including 1alpha,25(OH)(2)D-3 to support osteoclast differentiation from their precursors. Osteoclast precursors which express receptor activator of NF-kappaB (RANK) recognize RANKL through cell-to-cell interaction with...
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