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Phytotherapy

Isoflavones have limited effects on bone metabolism in estrogen-depleted rats

Published in Women's Health Weekly, March 27th, 2003

Isoflavones have limited effects on bone metabolism in estrogen-depleted rats.

"To examine a potential role for phytoestrogens in postmenopasual bone loss, the ovariectomized (OVX) rat model has been used to investigate whether lower than previously used doses of isoflavones are beneficial in impeding ovarian hormone deficiency-associated bone loss," according to research from the United States.

"In this study, 32 90-day-old Sprague-Dawley rats were randomly divided into four groups and fed a semipurified diet with or without isoflavones for 40 days. The treatment groups were sham-operated (sham), OVX, OVX+ isoflavones (0. 575 mg/g of dietary...

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