Breast Cancer

Cyclooxygenase-2 is more highly expressed than in more benign breast diseases

Published in Women's Health Weekly, May 22nd, 2003

Cyclooxygenase-2 expression was generally higher in patients with breast carcinoma than in those with fibroadenoma and fibrocystic breasts.

According to a study from Croatia, "Numerous studies have demonstrated that the levels of cyclooxygenase (COX), the enzyme that catalyzes the conversion of arachidonic acid to prostaglandin H-2, and of prostaglandins are higher in various tumors and cells during inflammation than in normal tissues.

"The aim of the present study was to analyze whether COX-2 isoform expression was noticeably higher in fine-needle aspirates (FNA) from breast carcinoma than in FNA from fibroadenoma and fibrocystic breast tissue....

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Source: Women's Health Weekly (2003-05-22)

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