Oncology
Thymidine phosphorylase signals control the angiogenesis of ovarian cancer
Published in Women's Health Weekly, June 5th, 2003
According to recent research published in the International Journal of Oncology, "metastasis or progression of ovarian cancer cells is known to be due to the action of various angiogenic factors. We determined the expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor (TP/PDECGF) and vascular endothelial growth factor (VEGF) in cell lines established from 3 serous adenocarcinomas, 3 clear cell carcinomas and 2 mucinous carcinomas of the human ovary."
"TP activity and the TP mRNA level were much higher in the serous adenocarcinoma cells...
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