Sexually Transmitted Disease
Treponema pallidum has a laminin-binding protein, Tp0751
Published in Women's Health Weekly, July 17th, 2003
According to recent research published in the journal Infection and Immunity, "Host extracellular matrix (ECM) components represent ideal microbial adhesion targets that many pathogens use for colonization of tissues and initiation of infection. This study investigated the interaction of the spirochete Treponema pallidum with the ECM component laminin.
"To identify candidate laminin-binding adhesins, the T. pallidum genome was analyzed to predict open reading frames (ORF) that encode putative outer membrane proteins, as...
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