Osteoporosis
Low-dose contraceptives have a positive effect on bone turnover in young women
Published in Women's Health Weekly, July 31st, 2003
"In this prospective, controlled, randomized study, we compared the effect of a low-dose 21-day combined oral contraceptive (COC) containing 20 microgram ethinyl estradiol (EE) and 75 microgram gestodene (GTD) (Group A; n = 19) with an ultra-low-dose 2-day COC containing 15 microgram EE and 60 microgram GTD (Group B; n = 18) on bone turnover and bone mineral density (BMD) in young, fertile women. Nineteen healthy fertile women were used as untreated controls (Group C). At 3, 6, 9 and 12 months of the study serum osteocalcin (BGP), urinary pyridinoline (PYD) and deoxypyridinoline (D-PYD) were...
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