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Mental Health

Genetic differences partly account for higher incidence of depression in women

Published in Women's Health Weekly, August 7th, 2003

Depression is the second-leading cause of disability worldwide, affecting nearly 10% of the population.

According to George S. Zubenko, MD, PhD, professor of psychiatry at the University of Pittsburgh School of Medicine and adjunct professor of biology at Carnegie Mellon University, women are twice as likely as men to develop depression, and genetic differences appear to account for some of that disparity.

These latest results, published in Molecular Psychiatry (2003;8(6):611-618) build on research published by Zubenko and his team in October 2002 that identified a small region of chromosome 2 - equal to 0.01% of the human genome - as the...

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