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Breast Cancer

Breast cell invasive potential relates to myoepithelial phenotype

Published in Women's Health Weekly, August 28th, 2003

Breast cell invasive potential relates to the myoepithelial phenotype.

According to recent research published in the International Journal of Cancer, "On the basis of marker profile, the majority of breast carcinomas are thought to be derived from luminal epithelial cells; however, a subgroup of tumors with more mesenchymal characteristics are associated with a worse prognosis.

"The hypothesis of our study is that some breast carcinomas exhibit myoepithelial rather than pure mesenchymal differentiation and that acquisition of myoepithelial characteristics confers an aggressive phenotype," wrote L.A. Gordon and colleagues, University of...

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