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Mental Health

APOE genotype joins fetal or neonatal malnutrition as a risk for schizophrenia

Published in Women's Health Weekly, September 4th, 2003

APOE genotype joins fetal or neonatal malnutrition as a risk for schizophrenia.

"Five hundred and seventy nine Chinese patients with schizophrenia who met DSMIV criteria for the disorder were genotyped for alleles epsilon2,3,4 of apolipoprotein E (APOE) gene. All were recruited from inpatients and outpatients attending a large mental health center in Shanghai. Results were compared to APOE data on 1528 controls drawn from the same area," scientists writing in the journal Schizophrenia Research reported.

"Major differences in APOE genotype ratios and allele frequencies were observed between the patients and controls. The patients with...

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