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Gynecology

Estradiol implants don't improve the urge syndrome in postmenopausal women

Published in Women's Health Weekly, September 4th, 2003

Estradiol implants don't improve the urge syndrome in postmenopausal women.

"The aim of this prospective double-blind randomized placebo-controlled trial was to determine the effect of systemic estrogen on the 'urge syndrome' in postmenopausal women. The trial took place in a tertiary referral urogynecology unit. Postmenopausal women with the 'urge syndrome' were randomly allocated to receive a 25 mg 17beta-estradiol implant or placebo implant," scientists in England reported.

"Serum estradiol levels and endometrial thickness were measured on entry to the trial and at 1, 3 and 6 months. The following outcome measures were employed:...

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