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Breast Cancer

Genetic clues may show which women face risk from HRT

Published in Women's Health Weekly, October 9th, 2003

A genetic clue may eventually help physicians identify certain women who would face an increased risk of breast cancer from using hormone replacement therapy.

Researchers from the Keck School of Medicine of the University of Southern California obtained mammograms on more than 200 women and found that those with a genetic variant developed denser breast tissue after using estrogen and progestin therapy than women without the variant.

Mammographic density is a risk factor for breast cancer and has been proposed as a marker for breast cancer risk.

"Our research is promising. We already know that only some women who use hormone...

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