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Gynecology

Phase I-IIa interim data of ovarian cancer treatment released

Published in Women's Health Weekly, November 20th, 2003

Telik, Inc., (TELK) announced positive interim results from its Phase I-IIa clinical trial using escalating doses of Telcyta in combination with carboplatin in patients with platinum refractory or resistant ovarian cancer.

At the time of interim analysis, eight patients being treated at Telcyta (500 mg/m2) and carboplatin (AUC 5 or 6) are evaluable. All patients have platinum refractory or resistant disease. Five of the eight evaluable patients (63%) have objective tumor responses by the RECIST criteria, including one complete response.

The overall disease stabilization rate is 88%. Telcyta in combination with carboplatin has been well-tolerated in...

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