Endometrial Cancer
11q23-24 loss is associated with chromosomal instability in endometrial cancer
Published in Women's Health Weekly, December 18th, 2003
"A loss of the DNA copy number at chromosomal region 11q23-24 as detected by comparative genomic hybridization (CGH) is a marker of poor prognosis in patients with endometrial cancer," scientists in Japan report.
"Malignant tumors display genetic instability, which is classified into two types: microsatellite instability (MIN) and chromosomal instability (CIN). In the present study, we examined whether there is a relation between loss of 11q23-24 and genetic instability in endometrial adenocarcinoma," wrote K. Kawasaki and colleagues, Yamaguchi...
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