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Breast Cancer

Researchers develop a mathematical modeling of comedo DCIS of the breast

Published in Women's Health Weekly, January 8th, 2004

Researchers show how the duct wall deforms as the tumor grows and how the progression of the tumor along the duct depends upon the stiffness of the wall.

"The growth of a tumor in a cylindrical duct with compliant walls is examined in order to model the early stages of ductal carcinoma in situ (DCIS) of the breast, the earliest known stage of breast cancer," scientists in England report.

"A nutrient-limited growth model is formulated, in which cell movement is described by a Stokes flow constitutive relation. The interactions between the expansive forces created by tumor cell proliferation and the stresses that develop in the compliant basement...

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