Preeclampsia
High PLA2 levels in decidual tissue may underlie acute atherosis
Published in Women's Health Weekly, January 22nd, 2004
According to recent research from Norway, "Decidual acute atherosis is associated with preeclampsia, but the underlying mechanism is still unclear."
"We have previously demonstrated elevated level of the oxidative stress marker 8-isoprostaglandin F-2alpha (8-isoprostane) and lipids in preeclamptic decidual tissue," noted A.C. Staff and coauthors at the University of Oslo. "Arachidonic acid (AA) in tissue phospholipids is a source for 8-isoprostane generation, and 8-isoprostane is liberated from tissue...
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