Obstetrics

Researchers identify enzyme that helps make uterus stretchy

Published in Women's Health Weekly, February 12th, 2004

The uterus is a wonder among organs, stretching to the size of a basketball to accommodate a growing baby, then rebounding neatly back to the pear-sized form it had before.

This ability is at the center of a report published in the February 2004 issue of Nature Genetics by Tiansen Li and colleagues at Harvard Medical School, who have identified an enzyme called LOX1, essential for the body to make and maintain the elastic fibers that keep our tissues taut and stretchy.

The researchers worked with mice in their study. Experimental mice lacking the enzyme LOX1 had loose and baggy skin several sizes too large and the females frequently suffered...

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Source: Women's Health Weekly (2004-02-12)

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