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Pediatrics

Bone mass tends to improve in thalassemic children at puberty

Published in Women's Health Weekly, February 19th, 2004

Bone mass tends to improve in thalassemic children at puberty.

According to researchers in Italy, "we evaluated bone mineral density (BMD) and bone turnover in 22 homozygous prepubertal beta-thalassemic patients treated with desferrioxamine. Ten patients underwent treatment with desferrioxamine for the whole study period, while 12 patients stopped desferrioxamine and were then treated with deferiprone (L1). Lumbar and femoral BMD and bone metabolism markers were examined at baseline and after 1 and 3 years of follow up."

"All patients were prepubertal at baseline and they all became pubertal over the 3 years of follow up. At baseline, the mean lumbar...

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