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Vitamin D receptor gene polymorphisms don't associate with osteomalacia

Published in Women's Health Weekly, February 19th, 2004

Vitamin D receptor gene polymorphisms don't associate with osteomalacia.

"Vitamin D receptor (VDR) gene polymorphism has been reported to be a determinant of bone formation and intestinal calcium absorption. We carried out this study to assess the role of VDR gene polymorphism in the pathogenesis of osteomalacia. We investigated BsmI polymorphisms in the gene encoding the 1,25 dihydroxyvitamin D receptor in 38 patients with osteomalacia and 31 healthy controls, along with examination of serum calcium, phosphorus, alkaline phosphatase, parathyroid hormone, and 25 hydroxyvitamin D levels," investigators in Turkey report.

"VDR allelic variants were: BB,...

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