Published in Women's Health Weekly, February 19th, 2004
"Nitric oxide synthase (NOS) and arginase have been shown to regulate nitric oxide (NO) production reciprocally in genital tissues. In animal models, NO is an important regulator of vaginal blood flow and vaginal wall contractility. In this study, we investigated the modulation of NOS and arginase activities by estrogens and androgens in the proximal and distal rabbit vagina," investigators in the United States report.
"In intact control animals, total NOS activity was higher in the proximal (528±78 pmol/mg protein) than the distal (391±44 pmol/mg protein) vagina....
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