Candida
ER packaging chaperone determines virulence of Candida albicans
Published in Women's Health Weekly, March 4th, 2004
"The Candida albicans CSH3 gene encodes a functional and structural homologue of Shr3p, a yeast protein that is specifically required for proper uptake and sensing of extracellular amino acids in Saccharomyces cerevisiae. A Candida csh3Delta/csh3Delta null mutant has a reduced capacity to take up amino acids, and is unable to switch morphologies on solid and in liquid media in response to inducing amino acids," researchers in Sweden report.
"CSH3/csh3Delta heterozygous strains display normal amino acid induced...
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