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Hormone Replacement Therapy

HRT can benefit women with menopausal symptoms, harm those without

Published in Women's Health Weekly, March 4th, 2004

Hormone replacement therapy (HRT) can help women experiencing menopausal symptoms, but women free of menopause-related symptoms should not use HRT, researchers say.

Researchers at Leicester University, U.K., carried out a clinical decision analysis on the benefits and harms of HRT, based on the best currently available evidence. The study population was white women in the United Kingdom, aged 50, with or without menopausal symptoms, who had used combined HRT for 5 years.

In women free of menopausal symptoms, the analysis showed a net harm associated with HRT use, which increased with increasing risk of breast cancer. However, it showed HRT to be on...

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