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Cancer Therapy

Preclinical data supports utility of INGN 241 combination regimens

Published in Women's Health Weekly, March 18th, 2004

Three abstracts evaluating the role of mda-7/IL-24, the active ingredient in Introgen Therapeutics' (INGN) INGN 241, in models of lung and breast cancer were presented at the Society of University Surgeons 65th annual meeting.

Introgen has completed a phase I/II clinical trial with INGN 241 and the data indicates that the therapy has demonstrated activity as a monotherapy in several cancer indications. Due to the multifunctional activity of mda-7/IL-24, which acts as a tumor suppressor, a potent inhibitor of angiogenesis, and an immunostimulating cytokine, INGN 241 may have broad utility as a monotherapy or as a component of combination regimens in a variety of cancer...

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