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Hematology

Hormone replacement therapy doesn't restore bone mass in thalassemic women

Published in Women's Health Weekly, March 25th, 2004

Hormone replacement therapy doesn't restore bone mass in thalassemic women.

According to scientists in Italy, "we studied bone mass and metabolism in 30 adult women (age 28.5±1.3) with thalassemia major (TM) and evaluated whether prolonged hormone replacement therapy (HRT) was able to optimize bone accrual."

"TM patients had reduced bone mass, increased bone turnover and lower serum gonadotropin and estradiol levels compared with 10 normal women of similar age. A significant correlation was found between bone mass and sex hormone levels," indicated E. Carmina and colleagues, University of Palermo, Department of Clinical Medicine and Emerging...

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