Endocrinology
Novel tissue-restricted angiogenic factors regulate steroidogenic function
Published in Women's Health Weekly, May 6th, 2004
"A novel family of angiogenic mitogens have been recently characterized. Endocrine gland-derived vascular endothelial growth factor (EG-VEGF), and the mammalian homologue of Bombina variegata peptide 8 (130), are two highly related endothelial cell mitogens and chemotactic factors with restricted expression profiles and selective endothelial cell activity. These peptides share two cognate G-protein coupled receptors," researchers in the United States report.
"The expression of human EG-VEGF occurs predominantly in steroidogenic glands. Consistent with such an...
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