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Parkinson Disease Risk Factor

Central obesity increases risk of Parkinson disease

Published in Women's Health Weekly, May 13th, 2004

Central obesity increases the risk of Parkinson disease.

"Dopamine is involved in the regulation of food intake, and obese persons have decreased dopamine D2 receptor availability in the striatum. Furthermore, midlife triceps skinfold thickness has been found to be positively associated with the risk of Parkinson disease (PD) among Japanese-American men in Hawaii. The authors prospectively investigated whether obesity was associated with PD risk in two large cohorts of U.S. men and women," scientists writing in the American Journal of Epidemiology report.

"They documented 249 cases of PD in men (1986-2000) and 202 cases in women (1976-1998),"...

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