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Breast Cancer

Ring finger protein RNF11 important target for novel cancer therapies

Published in Women's Health Weekly, May 13th, 2004

Ring finger protein RNF11 may be an important target for novel cancer therapies.

"The identification of novel tumor-associated genes represents an important area of cancer research. To that end," a "number of genes whose expression is altered in breast tumors" have been discovered. One of these genes has been identified as the ring finger protein 11 (RNF11) and its expression is elevated in breast and prostate cancer," scientists in Canada wrote.

"The RNF11 gene encodes a 154 amino-acid protein that contains a ring finger and a PY motif. RNF11 is capable of binding numerous proteins, which encompass a wide variety of cellular pathways and mechanisms....

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