Women's Health Weekly
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Environmental Health
Brief exposure to chlorpyrifos during neurulation affects brain development
May 13th, 2004
Brief exposure to chlorpyrifos during neurulation affects brain development. According to recent research published in the journal Neurotoxicology and Teratology, "the widely used organophosphate insecticide, chlorpyrifos (CPF), elicits neurobehavioral abnormalities after apparently subtoxic neonatal exposures. In the current study, we administered 1 or 5 mg/kg/day of CPF to pregnant rats on gestational days 9-12, the embryonic phase spanning formation and closure of the neural tube. Although there were no effects on growth or viability, offspring showed behavioral abnormalities when tested in adolescence and adulthood. "In the CPF-exposed...
Source: Women's Health Weekly (2004-05-13)
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