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Endocrinology

Taurine uptake affected by estradiol in endometrial tumor cells in vitro

Published in Women's Health Weekly, May 20th, 2004

Taurine uptake is affected by estradiol in endometrial tumor cells in vitro.

"The general properties of the taurine uptake in human endometrial tumoral Ishikawa cells were similar to those usually found in other tissues. Uptake was notably affected by the oxygen pressure, being higher at the physiological pO2 of the endometrium (40 mm Hg, equivalent to 5% O2 ) compared to that used under standard experimental culture conditions (160 mm Hg or 20% O2 )," wrote scientists in France.

"Uptake of taurine was also density-dependent in Ishikawa cells and was significantly decreased at confluence. Uptake regulation by PKC...

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