AIDS/HIV Transmission
AZT causes pattern of mutations in Tk gene of mice treated as neonates
Published in Women's Health Weekly, May 27th, 2004
According to recent research from the United States, "Mother-to-child transmission of the human immunodeficiency virus (HIV) is reduced by perinatal treatment with the antiretroviral nucleoside analogue 3'-azido-3-deoxythymidine (AZT, zidovudine). AZT, however, is genotoxic and carcinogenic in mice when administered either transplacentally or neonatally, suggesting a possible cancer risk for children later in life.
"In a previous study, we found that treating B6C3F1/Tk+/- mice on postnatal days 1...
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