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Obstetrics

Radioimmunoassay developed to measure 3,3'-T2S in maternal serum

Published in Women's Health Weekly, June 17th, 2004

A radioimmunoassay was developed to measure 3,3'-T2 S in maternal serum.

"Data suggesting that (1) sulfation of the phenolic hydroxyl of iodothyronines plays an important role in thyroid hormone metabolism and (2) maternal serum 3,3'-diiodothyronone sulfate (3,3'-T2 S) may reflect on the status of fetal thyroid function stimulated us to develop a radioimmunoassay (RIA) for measurement of T2 S. Our T2 S RIA is highly sensitive, practical, and reproducible," wrote scientists at the University of California Los Angeles.

"T4 S, TA and T1 S crossreacted 3.1%, 0.81%, and 5.3%, respectively;...

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