Breast Cancer
Concordance between HER-2 testing methods determined
Published in Women's Health Weekly, June 24th, 2004
In a recent study, scientists in New York "analyzed concordance between immunohistochemical analysis and fluorescence in situ hybridization (FISH) in HER-2 status and studied the effect of dual-color (D-FISH) vs. single-color FISH (S-FISH) scoring on the assignment of tumors to amplified or nonamplified categories."
"The assays were performed on formalin-fixed, paraffin-embedded sections of 2,279 invasive breast carcinomas," noted P. Lal and coauthors at the Memorial Sloan-Kettering Cancer Center. "Immunohistochemical results were interpreted as negative (0, 1+) or...
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