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Immunology

Yo-yo dieting may have a long-term negative effect on immune function

Published in Women's Health Weekly, June 24th, 2004

Yo-yo dieting, in which a person repeatedly loses and regains weight, may have a lasting negative impact on immune function.

Conversely, maintaining the same weight over time appears to have a positive effect on the immune system, report Cornelia Ulrich, PhD, Fred Hutchinson Cancer Research Center, Seattle, and colleagues in the June 2004 issue of the Journal of the American Dietetic Association.

Ulrich and colleagues at Fred Hutchinson and the University of Washington found that long-term immune function decreases in proportion to how many times a woman reportedly intentionally loses weight. They also found that immune function, as measured...

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